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What Is Sleep Hygiene? 11 Steps to a Better Night’s Sleep

Nothing is better than a good night’s sleep. But while we all wish we could sleep well every night, about 1 in 3 people suffer from mild to severe insomnia. One of the leading factors that can cause insomnia is poor sleep hygiene. Sleep hygiene refers to the routine you establish before bedtime, which can…

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NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR

NMN is synthesized from nicotinamide, a form of water-soluble vitamin B3, and 50-phosphoribosyl-1-pyrophosphate (PRPP), by NAMPT, the rate-limiting NAD+ biosynthetic enzyme in mam- mals (Figure 1A) (Imai and Yoshino, 2013; Revollo et al., 2004; Wang et al., 2006). NMN is also synthesized from NR via an NRK-mediated phosphorylation reaction, which is discussed further in the…

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