Nicotinamide Mononucleotide is hailed as the “Fountain of Youth” due to its anti-aging properties. This is backed up by scientific research and evidence from the laboratories. It is a part of the nucleotides family and is found in many foods. But how much should one consume NMN and are there any risks involved? See below to find out more.
When tests were taken on the laboratory mice having diet-related diabetes, recovery was observed. The oral consumption of NMN resulted in an improved insulin secretion along with better sensitivity to the insulin. This positive impact was seen after just one dose.
2- Alzheimer’s disorder
This is an age-related neurological condition. When NMN and Nicotinamide Riboside were administered in the mice, mental processes such as motor control, memory retention, thought formation and learning were enhanced to a great extent. Genes which play a big role in the formation of brain tissues were steadily increased as well. Apart from this, neuro-inflammation and beta-amyloid plaque was reduced by Nicotinamide Mononucleotide. The reason why the nucleotide is so adept at treating brain decline is because it can easily surpass the barrier between blood and brain.
3- Telomere length
The tails of the DNA code situated at the bottom of chromosome is known as Telomere. These tails shorten in length as the age increases due to the duplication of the chromosome. This leads to a death of cells eventually. Tests have revealed that by giving NMN dosage to mice, the length of Telomere was maximized in the liver cells.
The side effects usually depend on the health condition of the person. Moreover, if the patient has been involved with taking drugs and other supplements, side effects will be according to that. Generally, the safety profile of nicotinamide
mononucleotide is not determined till date because there are not many clinical studies on it. However, numerous researches have been carried on mice which shows that the dosage of NMN poses no side effects even with high amounts of administration.
There is no specified dosage of NMN prescribed because the FDA has not approved it for any condition. The companies which manufacture nicotinamide mononucleotide give their individual unofficial dosage which is made by trial and error. Therefore, do not consume any NMN Supplement before taking an advise from your doctor.
Usually, it is safe to consume a few hundred mg of nicotinamide mononucleotide per day. The most famous dosage is 125 mg taken twice every day. The time span should be around 8 weeks depending on the condition of the person.
A concern that was raised regarding the cancer patients taking NMN supplements is that since Nicotinamide Mononucleotide produces new blood vessels, it can also direct the blood flow to tumors and promote angiogenesis. This means that the tumors will grow abundantly and the body will resist medication. But the study of Dr. David Sinclair reported that the influence of NMN on angiogenesis was positive. It improved the vascular health to normal and cancer was not made worse.